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Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells
Intrinsic and extrinsic apoptotic pathways converge to activate common downstream executioner caspases (caspase-3, -6, and -7), resulting in cell death. In chronic lymphocytic leukemia (CLL), neoplastic B cells evade apoptosis owing to the overexpression of survival proteins. We hypothesized that di...
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| Publicado no: | Blood |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326772/ https://ncbi.nlm.nih.gov/pubmed/25538042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-546796 |
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