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Population pharmacokinetics and optimal design of paediatric studies for famciclovir

AIMS: To develop a population pharmacokinetic model for penciclovir (famciclovir is a prodrug of penciclovir) in adults and children and suggest an appropriate dose for children. Furthermore, to develop a limited sampling design based on sampling windows for three different paediatric age groups (1–...

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Autors principals: Ogungbenro, Kayode, Matthews, Ivan, Looby, Michael, Kaiser, Guenther, Graham, Gordon, Aarons, Leon
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780280/
https://ncbi.nlm.nih.gov/pubmed/19843058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03479.x
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