Φορτώνει......
Empirical and Semi-Mechanistic Modelling of Double-Peaked Pharmacokinetic Profile Phenomenon Due to Gastric Emptying
Models have been developed to explain double-peaked plasma concentration-time profiles using mechanisms such as variable absorption and enterohepatic recirculation. Interruption of gastric emptying has also been shown to produce double-peaks, and this work proposes models for analysis of such data....
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | AAPS J |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer US
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287295/ https://ncbi.nlm.nih.gov/pubmed/25413723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9693-5 |
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