Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data

Whole-body physiologically based pharmacokinetic (PBPK) models are increasingly used in drug development for their ability to predict drug concentrations in clinically relevant tissues and to extrapolate across species, experimental conditions and sub-populations. A whole-body PBPK model can be fitt...

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Xehetasun bibliografikoak
Argitaratua izan da:AAPS J
Egile Nagusiak: Wendling, Thierry, Tsamandouras, Nikolaos, Dumitras, Swati, Pigeolet, Etienne, Ogungbenro, Kayode, Aarons, Leon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706293/
https://ncbi.nlm.nih.gov/pubmed/26538125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9840-7
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