Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data

Whole-body physiologically based pharmacokinetic (PBPK) models are increasingly used in drug development for their ability to predict drug concentrations in clinically relevant tissues and to extrapolate across species, experimental conditions and sub-populations. A whole-body PBPK model can be fitt...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:AAPS J
Asıl Yazarlar: Wendling, Thierry, Tsamandouras, Nikolaos, Dumitras, Swati, Pigeolet, Etienne, Ogungbenro, Kayode, Aarons, Leon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706293/
https://ncbi.nlm.nih.gov/pubmed/26538125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9840-7
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller