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A class I ligase ribozyme with reduced Mg(2+) dependence: Selection, sequence analysis, and identification of functional tertiary interactions

The class I ligase was among the first ribozymes to have been isolated from random sequences and represents the catalytic core of several RNA-directed RNA polymerase ribozymes. The ligase is also notable for its catalytic efficiency and structural complexity. Here, we report an improved version of t...

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Détails bibliographiques
Auteurs principaux: Bagby, Sarah C., Bergman, Nicholas H., Shechner, David M., Yen, Catherine, Bartel, David P.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779684/
https://ncbi.nlm.nih.gov/pubmed/19946040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1912509
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