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A class I ligase ribozyme with reduced Mg(2+) dependence: Selection, sequence analysis, and identification of functional tertiary interactions
The class I ligase was among the first ribozymes to have been isolated from random sequences and represents the catalytic core of several RNA-directed RNA polymerase ribozymes. The ligase is also notable for its catalytic efficiency and structural complexity. Here, we report an improved version of t...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779684/ https://ncbi.nlm.nih.gov/pubmed/19946040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1912509 |
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