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GAMT, a p53-Inducible Modulator of Apoptosis, Is Critical for the Adaptive Response to Nutrient Stress

The p53 tumor suppressor protein has a well-established role in cell fate decision-making processes. However, recent discoveries indicate that p53 has a non-tumor-suppressive role. Here, we identify GAMT (guanidinoacetate methyltransferase), an enzyme involved in creatine synthesis, as a p53 target...

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Autors principals: Ide, Takao, Brown-Endres, Lauren, Chu, Kiki, Ongusaha, Pat P., Ohtsuka, Takao, El-Deiry, Wafik S., Aaronson, Stuart A., Lee, Sam W.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779531/
https://ncbi.nlm.nih.gov/pubmed/19917247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.031
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