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CDIP, a novel pro-apoptotic gene, regulates TNFα-mediated apoptosis in a p53-dependent manner

We have identified a novel pro-apoptotic p53 target gene named CDIP (Cell Death Involved p53-target). Inhibition of CDIP abrogates p53-mediated apoptotic responses, demonstrating that CDIP is an important p53 apoptotic effector. CDIP itself potently induces apoptosis that is associated with caspase-...

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Bibliografski detalji
Glavni autori: Brown, Lauren, Ongusaha, Pat P, Kim, Hyung-Gu, Nuti, Shanthy, Mandinova, Anna, Lee, Ji Won, Khosravi-Far, Roya, Aaronson, Stuart A, Lee, Sam W
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933410/
https://ncbi.nlm.nih.gov/pubmed/17599062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601779
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