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Expression of the p53 target CDIP correlates with sensitivity to TNF-alpha induced apoptosis in cancer cells

TNFα is a pleiotropic cytokine that signals for both survival and apoptotic cell fates. It is still unclear that the dual role of TNFα can be regulated in cancer cells. We previously described an apoptotic pathway involving p53→CDIP→TNFα that was activated in response to genotoxic stress. This pathw...

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Hlavní autoři: Brown-Endres, Lauren, Schoenfeld, David, Tian, Fang, Kim, Hyung-Gu, Namba, Takushi, Muñoz-Fontela, César, Mandinova, Anna, Aaronson, Stuart A., Lee, Sam W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349239/
https://ncbi.nlm.nih.gov/pubmed/22549949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3369
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