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Dual Role of p53 in Innate Antiviral Immunity

Tumor suppressor p53 is widely known as ‘the guardian of the genome’ due to its ability to prevent the emergence of transformed cells by the induction of cell cycle arrest and apoptosis. However, recent studies indicate that p53 is also a direct transcriptional target of type I interferons (IFNs) an...

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Autores principales: Rivas, Carmen, Aaronson, Stuart A., Munoz-Fontela, Cesar
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185551/
https://ncbi.nlm.nih.gov/pubmed/21994612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2010298
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