Dual oxidase 1 promotes antiviral innate immunity

Dual oxidase 1 (DUOX1) is an NADPH oxidase that is highly expre-ssed in respiratory epithelial cells and produces H(2)O(2) in the airway lumen. While a line of prior in vitro observations suggested that DUOX1 works in partnership with an airway peroxidase, lactoperoxidase (LPO), to produce antimicro...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sarr, Demba, Gingerich, Aaron D., Asthiwi, Nuha Milad, Almutairi, Faris, Sautto, Giuseppe A., Ecker, Jeffrey, Nagy, Tamás, Kilgore, Matthew B., Chandler, Joshua D., Ross, Ted M., Tripp, Ralph A., Rada, Balázs
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256044/
https://ncbi.nlm.nih.gov/pubmed/34168077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017130118
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