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Oxidative innate immune defenses by Nox/Duox family NADPH Oxidases

The importance of reactive oxygen species (ROS) in innate immunity was first recognized in professional phagocytes undergoing a “respiratory burst” upon activation. This robust oxygen consumption is related to a superoxide-generating enzyme, the phagocytic NADPH oxidase (Nox2 or phox). The oxidase i...

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Detalhes bibliográficos
Main Authors: Rada, Balázs, Leto, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776633/
https://ncbi.nlm.nih.gov/pubmed/18511861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000136357
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