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p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus

Several direct target genes of the p53 tumor suppressor have been identified within pathways involved in viral sensing, cytokine production, and inflammation, suggesting a potential role of p53 in antiviral immunity. The increasing need to identify immune factors to devise host-targeted therapies ag...

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Hlavní autoři: Muñoz-Fontela, César, Pazos, Michael, Delgado, Igotz, Murk, William, Mungamuri, Sathish Kumar, Lee, Sam W., García-Sastre, Adolfo, Moran, Thomas M., Aaronson, Stuart A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275346/
https://ncbi.nlm.nih.gov/pubmed/22105999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101459
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