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MCL-1–dependent leukemia cells are more sensitive to chemotherapy than BCL-2–dependent counterparts
Myeloid cell leukemia sequence 1 (MCL-1) and B cell leukemia/lymphoma 2 (BCL-2) are anti-apoptotic proteins in the BCL-2 protein family often expressed in cancer. To compare the function of MCL-1 and BCL-2 in maintaining cancer survival, we constructed complementary mouse leukemia models based on Eμ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779245/ https://ncbi.nlm.nih.gov/pubmed/19948485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904049 |
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