Загрузка...

MCL-1–dependent leukemia cells are more sensitive to chemotherapy than BCL-2–dependent counterparts

Myeloid cell leukemia sequence 1 (MCL-1) and B cell leukemia/lymphoma 2 (BCL-2) are anti-apoptotic proteins in the BCL-2 protein family often expressed in cancer. To compare the function of MCL-1 and BCL-2 in maintaining cancer survival, we constructed complementary mouse leukemia models based on Eμ...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Brunelle, Joslyn K., Ryan, Jeremy, Yecies, Derek, Opferman, Joseph T., Letai, Anthony
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779245/
https://ncbi.nlm.nih.gov/pubmed/19948485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904049
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!