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BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia
Cancer cells acquire disruptions in normal signal transduction pathways and homeostatic mechanisms that would trigger apoptosis in normal cells. These abnormalities include genomic instability, oncogene activation, and growth factor independent proliferation. Therefore, cancer cells likely require a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234061/ https://ncbi.nlm.nih.gov/pubmed/18056841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-098012 |
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