BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia

Cancer cells acquire disruptions in normal signal transduction pathways and homeostatic mechanisms that would trigger apoptosis in normal cells. These abnormalities include genomic instability, oncogene activation, and growth factor independent proliferation. Therefore, cancer cells likely require a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Del Gaizo Moore, Victoria, Schlis, Krysta D., Sallan, Stephen E., Armstrong, Scott A., Letai, Anthony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2008
Gaiak:
Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234061/
https://ncbi.nlm.nih.gov/pubmed/18056841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-098012
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