AAV3-mediated Transfer and Expression of the Pyruvate Dehydrogenase E1 alpha Subunit Gene Causes Metabolic Remodeling and Apoptosis of Human Liver Cancer Cells

Most cancers rely disproportionately on glycolysis for energy even in the presence of adequate oxygen supply, a condition known as “aerobic glycolysis”, or the Warburg effect. Pharmacological reversal of the Warburg effect has been shown to cause selective apoptosis of tumor cells, presumably by sti...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Glushakova, Lyudmyla G., Lisankie, Matthew J., Eruslanov, Evgeniy B., Ojano-Dirain, Carolyn, Zolotukhin, Irene, Liu, Chen, Srivastava, Arun, Stacpoole, Peter W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779054/
https://ncbi.nlm.nih.gov/pubmed/19586787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2009.05.010
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы