AAV3-mediated Transfer and Expression of the Pyruvate Dehydrogenase E1 alpha Subunit Gene Causes Metabolic Remodeling and Apoptosis of Human Liver Cancer Cells

Most cancers rely disproportionately on glycolysis for energy even in the presence of adequate oxygen supply, a condition known as “aerobic glycolysis”, or the Warburg effect. Pharmacological reversal of the Warburg effect has been shown to cause selective apoptosis of tumor cells, presumably by sti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Glushakova, Lyudmyla G., Lisankie, Matthew J., Eruslanov, Evgeniy B., Ojano-Dirain, Carolyn, Zolotukhin, Irene, Liu, Chen, Srivastava, Arun, Stacpoole, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779054/
https://ncbi.nlm.nih.gov/pubmed/19586787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2009.05.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados