A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

Mental retardation in Down syndrome (DS), the most frequent trisomy in humans, varies from moderate to severe. Several studies both in human and based on mouse models identified some regions of human chromosome 21 (Hsa21) as linked to cognitive deficits. However, other intervals such as the telomeri...

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Autori principali: Pereira, Patricia Lopes, Magnol, Laetitia, Sahún, Ignasi, Brault, Véronique, Duchon, Arnaud, Prandini, Paola, Gruart, Agnès, Bizot, Jean-Charles, Chadefaux-Vekemans, Bernadette, Deutsch, Samuel, Trovero, Fabrice, Delgado-García, José María, Antonarakis, Stylianos E., Dierssen, Mara, Herault, Yann
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778371/
https://ncbi.nlm.nih.gov/pubmed/19783846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp438
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