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Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome

Trisomy 21 is the prototype of human aneuploidies. Since its discovery in 1959, the hypothesis has been that overexpression of the ∼230 human chromosome 21 (Hsa21) genes result in the complex phenotype. However, the level of overexpression of Hsa21 genes in trisomic individuals is presently unknown....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lyle, Robert, Gehrig, Corinne, Neergaard-Henrichsen, Charlotte, Deutsch, Samuel, Antonarakis, Stylianos E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC442141/
https://ncbi.nlm.nih.gov/pubmed/15231743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2090904
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