Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome
Trisomy 21 is the prototype of human aneuploidies. Since its discovery in 1959, the hypothesis has been that overexpression of the ∼230 human chromosome 21 (Hsa21) genes result in the complex phenotype. However, the level of overexpression of Hsa21 genes in trisomic individuals is presently unknown....
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| Gepubliceerd in: | Genome Res |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15231743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.2090904 |
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