Intracisternal Gtf2i Gene Therapy Ameliorates Deficits in Cognition and Synaptic Plasticity of a Mouse Model of Williams–Beuren Syndrome

Por Borralleras, Cristina, Sahun, Ignasi, Pérez-Jurado, Luis A, Campuzano, Victoria
Publicado no Mol Ther (2015)

Targeting Dyrk1A with AAVshRNA Attenuates Motor Alterations in TgDyrk1A, a Mouse Model of Down Syndrome

Por Ortiz-Abalia, Jon, Sahún, Ignasi, Altafaj, Xavier, Andreu, Núria, Estivill, Xavier, Dierssen, Mara, Fillat, Cristina
Publicado em 2008

Dissociation between CA3–CA1 Synaptic Plasticity and Associative Learning in TgNTRK3 Transgenic Mice

Por Sahún, Ignasi, Delgado-García, José María, Amador-Arjona, Alejandro, Giralt, Albert, Alberch, Jordi, Dierssen, Mara, Gruart, Agnès
Publicado no J Neurosci (2007)

Cognition and Hippocampal Plasticity in the Mouse Is Altered by Monosomy of a Genomic Region Implicated in Down Syndrome

Por Sahún, Ignasi, Marechal, Damien, Pereira, Patricia Lopes, Nalesso, Valérie, Gruart, Agnes, Garcia, José Maria Delgado, Antonarakis, Stylianos E., Dierssen, Mara, Herault, Yann
Publicado em 2014

Overexpression of Reelin Prevents the Manifestation of Behavioral Phenotypes Related to Schizophrenia and Bipolar Disorder

Por Teixeira, Cátia M, Martín, Eduardo D, Sahún, Ignasi, Masachs, Nuria, Pujadas, Lluís, Corvelo, André, Bosch, Carles, Rossi, Daniela, Martinez, Albert, Maldonado, Rafael, Dierssen, Mara, Soriano, Eduardo
Publicado em 2011

Ceramide Levels Regulated by Carnitine Palmitoyltransferase 1C Control Dendritic Spine Maturation and Cognition

Por Carrasco, Patricia, Sahún, Ignasi, McDonald, Jerome, Ramírez, Sara, Jacas, Jordi, Gratacós, Esther, Sierra, Adriana Y., Serra, Dolors, Herrero, Laura, Acker-Palmer, Amparo, Hegardt, Fausto G., Dierssen, Mara, Casals, Núria
Publicado em 2012

Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Hspa13-App Region

Por Brault, Véronique, Duchon, Arnaud, Romestaing, Caroline, Sahun, Ignasi, Pothion, Stéphanie, Karout, Mona, Borel, Christelle, Dembele, Doulaye, Bizot, Jean-Charles, Messaddeq, Nadia, Sharp, Andrew J., Roussel, Damien, Antonarakis, Stylianos E, Dierssen, Mara, Hérault, Yann
Publicado no PLoS Genet (2015)

Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice

Por Dierssen, Mara, Fedrizzi, Laura, Gomez-Villafuertes, Rosa, de Lagran, María Martinez, Gutierrez-Adan, Alfonso, Sahún, Ignasi, Pintado, Belen, Oliveros, Juan C., Dopazo, Xose M., Gonzalez, Paz, Brini, Marisa, Mellström, Britt, Carafoli, Ernesto, Naranjo, Jose R.
Publicado em 2012

A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

Por Pereira, Patricia Lopes, Magnol, Laetitia, Sahún, Ignasi, Brault, Véronique, Duchon, Arnaud, Prandini, Paola, Gruart, Agnès, Bizot, Jean-Charles, Chadefaux-Vekemans, Bernadette, Deutsch, Samuel, Trovero, Fabrice, Delgado-García, José María, Antonarakis, Stylianos E., Dierssen, Mara, Herault, Yann
Publicado em 2009

Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome

Por Arranz, Juan, Balducci, Elisa, Arató, Krisztina, Sánchez-Elexpuru, Gentzane, Najas, Sònia, Parras, Alberto, Rebollo, Elena, Pijuan, Isabel, Erb, lonas, Verde, Gaetano, Sahun, Ignasi, Barallobre, Maria J., Lucas, José J., Sánchez, Marina P., de la Luna, Susana, Arbonés, Maria L.
Publicado no Neurobiol Dis (2019)

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss

Por Espino Guarch, Meritxell, Font-Llitjós, Mariona, Murillo-Cuesta, Silvia, Errasti- Murugarren, Ekaitz, Celaya, Adelaida M, Girotto, Giorgia, Vuckovic, Dragana, Mezzavilla, Massimo, Vilches, Clara, Bodoy, Susanna, Sahún, Ignasi, González, Laura, Prat, Esther, Zorzano, Antonio, Dierssen, Mara, Varela-Nieto, Isabel, Gasparini, Paolo, Palacín, Manuel, Nunes, Virginia
Publicado no eLife (2018)

DREAM Controls the On/Off Switch of Specific Activity-Dependent Transcription Pathways

Por Mellström, Britt, Sahún, Ignasi, Ruiz-Nuño, Ana, Murtra, Patricia, Gomez-Villafuertes, Rosa, Savignac, Magali, Oliveros, Juan C., Gonzalez, Paz, Kastanauskaite, Asta, Knafo, Shira, Zhuo, Min, Higuera-Matas, Alejandro, Errington, Michael L., Maldonado, Rafael, DeFelipe, Javier, Jefferys, John G. R., Bliss, Tim V. P., Dierssen, Mara, Naranjo, Jose R.
Publicado em 2014