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MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorectal cancer families

AIM: To detect the MLH1 gene promoter germline-methylation in probands of Chinese hereditary nonpolyposis colorectal cancer (HNPCC), and to evaluate the role of methylation in MLH1 gene promoter and molecular genetics in screening for HNPCC. METHODS: The promoter germline methylation of MLH1 gene wa...

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Detalhes bibliográficos
Main Authors: Zhou, Heng-Hua, Yan, Shi-Yan, Zhou, Xiao-Yan, Du, Xiang, Zhang, Tai-Ming, Cai, Xu, Lu, Yong-Ming, Cai, San-Jun, Shi, Da-Ren
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778116/
https://ncbi.nlm.nih.gov/pubmed/19109866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.7329
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