Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families

AIM: To investigate the germline mutations of MSH6 gene in probands of Chinese hereditary non-polyposis colorectal cancer (HNPCC) families fulfilling different clinical criteria. METHODS: Germline mutations of MSH6 gene were detected by PCR-based DNA sequencing in 39 unrelated HNPCC probands fulfill...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Yan, Shi-Yan, Zhou, Xiao-Yan, Du, Xiang, Zhang, Tai-Ming, Lu, Yong-Ming, Cai, San-Jun, Xu, Xiao-Li, Yu, Bao-Hua, Zhou, Heng-Hua, Shi, Da-Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434628/
https://ncbi.nlm.nih.gov/pubmed/17854147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i37.5021
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