Germline mutation analysis of hPMS2 gene in Chinese families with hereditary nonpolyposis colorectal cancer

AIM: To study the germline mutation of hPMS2 gene in 26 unrelated Chinese hereditary nonpolyposis colorectal cancer (HNPCC) probands and to fulfill the screening strategy for HNPCC in Chinese. METHODS: Genomic DNA was extracted from the peripheral blood. To avoid the interference of pseudogene in de...

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Detalhes bibliográficos
Main Authors: Sheng, Xia, Zhou, Heng-Hua, Zhou, Xiao-Yan, Du, Xiang, Zhang, Tai-Ming, Cai, San-Jun, Sheng, Wei-Qi, Shi, Da-Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng 2010
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Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921098/
https://ncbi.nlm.nih.gov/pubmed/20698049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i30.3847
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