Two novel germline mutations of MLH1 and investigation of their pathobiology in hereditary non-polyposis colorectal cancer families in China

AIM: To detect germline mutations of MLH1, and investigate microsatellite instability and expression of MLH1 in tumor tissues of hereditary non-polyposis colorectal cancer (HNPCC) with two novel germline mutations, and further investigate the pathobiology of the two novel mutations of MLH1. METHODS:...

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Hlavní autoři: Wang, Chao-Fu, Zhou, Xiao-Yan, Zhang, Tai-Ming, Xu, Ye, Cai, San-Jun, Shi, Da-Ren
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2007
Témata:
Rapid Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171239/
https://ncbi.nlm.nih.gov/pubmed/18069769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i46.6254
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