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Diagnostic Application of hMLH1 Methylation in Hereditary Non-Polyposis Colorectal Cancer

Colorectal cancer (CRC) due to mismatch repair (MMR) defect has distinct characteristics among unselected CRCs. These CRCs are biologically less aggressive and, thus, showing better prognosis but less sensitive to the 5FU-based chemotherapy. CRCs with MMR defect derive from both hereditary and spora...

Täydet tiedot

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Bibliografiset tiedot
Päätekijä: Matsubara, Nagahide
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: IOS Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839271/
https://ncbi.nlm.nih.gov/pubmed/15528793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2004/371941
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