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Diagnostic Application of hMLH1 Methylation in Hereditary Non-Polyposis Colorectal Cancer
Colorectal cancer (CRC) due to mismatch repair (MMR) defect has distinct characteristics among unselected CRCs. These CRCs are biologically less aggressive and, thus, showing better prognosis but less sensitive to the 5FU-based chemotherapy. CRCs with MMR defect derive from both hereditary and spora...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
IOS Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839271/ https://ncbi.nlm.nih.gov/pubmed/15528793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2004/371941 |
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