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Autoxidation of Salvinorin A under Basic Conditions

Treatment of salvinorin A (1a) with KOH in MeOH gave the enedione 3, for which the dienone structure 7 was recently proposed. Also isolated, after methylation, were the seco-triesters 4a—c. A mechanism for this unusual series of autoxidations is proposed. Surprisingly, 4a showed weak affinity at the...

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Autors principals: Munro, Thomas A., Goetchius, Glenn W., Roth, Bryan L., Vortherms, Timothy A., Rizzacasa, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778035/
https://ncbi.nlm.nih.gov/pubmed/16292839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo051813e
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