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Alkylation of H-Phosphinate Esters under Basic Conditions

An efficient and general procedure was developed for the direct alkylation of H-phosphinate esters with LiHMDS at low temperature. The simplicity of the reaction allows the use of various H-phosphinate esters and takes place with a wide range of electrophiles. The approach can be employed to access...

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Autors principals: Abrunhosa-Thomas, Isabelle, Sellers, Claire E., Montchamp, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525801/
https://ncbi.nlm.nih.gov/pubmed/17352490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo062436o
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