Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

Myostatin is a highly conserved negative regulator of skeletal muscle growth. Loss of functional myostatin in cattle, mice, sheep, dogs, and humans results in increased muscle mass. The molecular mechanisms responsible for this increase in muscle growth are not fully understood. Previously, we have...

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Detalhes bibliográficos
Main Authors: Morissette, Michael R., Cook, Stuart A., Buranasombati, Cattleya, Rosenberg, Michael A., Rosenzweig, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Muscle Cell Biology and Cell Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777401/
https://ncbi.nlm.nih.gov/pubmed/19759331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00043.2009
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