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Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation

Muscle fibres are multinucleated post-mitotic cells that can change dramatically in size during adulthood. It has been debated whether muscle fibre hypertrophy requires activation and fusion of muscle stem cells, the satellite cells. Myostatin (MSTN) is a negative regulator of skeletal muscle growth...

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Autors principals: Wang, Qian, McPherron, Alexandra C
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447157/
https://ncbi.nlm.nih.gov/pubmed/22393251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.226001
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