Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

Myostatin is a highly conserved negative regulator of skeletal muscle growth. Loss of functional myostatin in cattle, mice, sheep, dogs, and humans results in increased muscle mass. The molecular mechanisms responsible for this increase in muscle growth are not fully understood. Previously, we have...

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Hlavní autoři: Morissette, Michael R., Cook, Stuart A., Buranasombati, Cattleya, Rosenberg, Michael A., Rosenzweig, Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
Muscle Cell Biology and Cell Motility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777401/
https://ncbi.nlm.nih.gov/pubmed/19759331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00043.2009
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