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Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

Myostatin is a highly conserved negative regulator of skeletal muscle growth. Loss of functional myostatin in cattle, mice, sheep, dogs, and humans results in increased muscle mass. The molecular mechanisms responsible for this increase in muscle growth are not fully understood. Previously, we have...

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Bibliografiske detaljer
Main Authors: Morissette, Michael R., Cook, Stuart A., Buranasombati, Cattleya, Rosenberg, Michael A., Rosenzweig, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777401/
https://ncbi.nlm.nih.gov/pubmed/19759331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00043.2009
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