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Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

Myostatin is a highly conserved negative regulator of skeletal muscle growth. Loss of functional myostatin in cattle, mice, sheep, dogs, and humans results in increased muscle mass. The molecular mechanisms responsible for this increase in muscle growth are not fully understood. Previously, we have...

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Détails bibliographiques
Auteurs principaux: Morissette, Michael R., Cook, Stuart A., Buranasombati, Cattleya, Rosenberg, Michael A., Rosenzweig, Anthony
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777401/
https://ncbi.nlm.nih.gov/pubmed/19759331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00043.2009
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