Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN

Signaling output of bone morphogenetic proteins (BMPs) is determined by two sets of opposing interactions, one with heterotetrameric complexes of cell surface receptors, the other with secreted antagonists that act as ligand traps. We identified two mutations (N445K,T) in patients with multiple syno...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Seemann, Petra, Brehm, Anja, König, Jana, Reissner, Carsten, Stricker, Sigmar, Kuss, Pia, Haupt, Julia, Renninger, Stephanie, Nickel, Joachim, Sebald, Walter, Groppe, Jay C., Plöger, Frank, Pohl, Jens, Schmidt-von Kegler, Mareen, Walther, Maria, Gassner, Ingmar, Rusu, Cristina, Janecke, Andreas R., Dathe, Katarina, Mundlos, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776984/
https://ncbi.nlm.nih.gov/pubmed/19956691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000747
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados