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Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease
BACKGROUND: Huntington's disease (HD) is an inherited neurogenerative disease caused by an abnormal expansion of glutamine repeats in the huntingtin protein. There is currently no treatment to prevent the neurodegeneration caused by this devastating disorder. Huntingtin has been shown to be a p...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776580/ https://ncbi.nlm.nih.gov/pubmed/19860865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-33 |
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