Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease

BACKGROUND: Huntington's disease (HD) is an inherited neurogenerative disease caused by an abnormal expansion of glutamine repeats in the huntingtin protein. There is currently no treatment to prevent the neurodegeneration caused by this devastating disorder. Huntingtin has been shown to be a p...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Pineda, Jose R, Pardo, Raúl, Zala, Diana, Yu, Hua, Humbert, Sandrine, Saudou, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776580/
https://ncbi.nlm.nih.gov/pubmed/19860865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-33
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items