Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation

A defect in microtubule (MT)-based transport contributes to the neuronal toxicity observed in Huntington's disease (HD). Histone deacetylase (HDAC) inhibitors show neuroprotective effects in this devastating neurodegenerative disorder. We report here that HDAC inhibitors, including trichostatin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Dompierre, Jim P., Godin, Juliette D., Charrin, Bénédicte C., Cordelières, Fabrice P., King, Stephen J., Humbert, Sandrine, Saudou, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672116/
https://ncbi.nlm.nih.gov/pubmed/17392473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0037-07.2007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados