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Interleukin-2 signals during priming are required for secondary expansion of CD8(+) memory T cells

Although interleukin-2 (IL-2) was initially characterized as the primary T-cell growth factor following in vitro activation1, less is known about its role in shaping T-cell responses to acute infections in vivo. The use of IL-2- or IL-2-receptor-deficient mice is problematic owing to their early dev...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Williams, Matthew A., Tyznik, Aaron J., Bevan, Michael J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776073/
https://ncbi.nlm.nih.gov/pubmed/16778891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04790
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