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Memory CD8(+) T cells exhibit increased antigen threshold requirements for recall proliferation

A hallmark of immunological memory is the ability of previously primed T cells to undergo rapid recall responses upon antigen reencounter. Classic work has suggested that memory T cells proliferate in response to lower doses of antigen than naive T cells and with reduced requirements for co-stimulat...

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Autori principali: Mehlhop-Williams, Erin R., Bevan, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920562/
https://ncbi.nlm.nih.gov/pubmed/24493801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131271
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