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CD4(+) T cells are required for the maintenance, not programming, of memory CD8(+) T cells after acute infection
Immunization in the absence of CD4(+) T cell help results in defective CD8(+) T cell memory, deficient recall responses and diminished protective immunity. Here we investigated at what stage during the immune response to pathogen CD4(+) T cells are essential in the promotion of functional CD8(+) T c...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776074/ https://ncbi.nlm.nih.gov/pubmed/15300249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1105 |
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