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Evidence for an association between TSH and IGF-1 receptors: A tale of two antigens implicated in Graves’ disease

TSH receptor (TSHR) plays a central role in regulating thyroid function and is targeted by IgGs in Graves’ disease (GD-IgG). Whether TSHR is involved in the pathogenesis of thyroid associated ophthalmopathy, the orbital manifestation of GD, remains uncertain. TSHR signaling overlaps with that of ins...

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Detalhes bibliográficos
Main Authors: Tsui, Shanli, Naik, Vibha, Hoa, Neil, Hwang, Catherine J., Afifyan, Nikoo F., Hikim, Amiya Sinha, Gianoukakis, Andrew G., Douglas, Raymond S., Smith, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775538/
https://ncbi.nlm.nih.gov/pubmed/18768899
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