Lataa...
Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
In vitro–transcribed mRNAs encoding physiologically important proteins have considerable potential for therapeutic applications. However, in its present form, mRNA is unfeasible for clinical use because of its labile and immunogenic nature. Here, we investigated whether incorporation of naturally mo...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775451/ https://ncbi.nlm.nih.gov/pubmed/18797453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.200 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|