Laddar...

Highly error-free role of DNA polymerase η in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells

Cyclobutane pyrimidine dimers (CPDs) constitute the most frequent UV-induced DNA photoproduct. However, it has remained unclear how human and other mammalian cells mitigate the mutagenic and carcinogenic potential of CPDs emanating from their replicative bypass. Here, we examine in human cells the r...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yoon, Jung-Hoon, Prakash, Louise, Prakash, Satya
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775276/
https://ncbi.nlm.nih.gov/pubmed/19822754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910121106
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!