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Error-free replicative bypass of (6–4) photoproducts by DNA polymerase ζ in mouse and human cells
The ultraviolet (UV)-induced (6–4) pyrimidine–pyrimidone photoproduct [(6–4) PP] confers a large structural distortion in DNA. Here we examine in human cells the roles of translesion synthesis (TLS) DNA polymerases (Pols) in promoting replication through a (6–4) TT photoproduct carried on a duplex p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807347/ https://ncbi.nlm.nih.gov/pubmed/20080950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1872810 |
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