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Modulation of mitochondrial bioenergetics in isolated guinea pig beating heart by potassium and lidocaine cardioplegia: implications for cardioprotection
Mitochondria are damaged by cardiac ischemia-reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against I/R injury. Guinea pig hearts (n=71) were perf...
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Main Authors: | , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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2009
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774837/ https://ncbi.nlm.nih.gov/pubmed/19620879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181b2b842 |
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