A comprehensive study of Sansalvamide A derivatives: the structure-activity relationships of 78 derivatives in 2 pancreatic cancer cell lines

We report an extensive structure-activity relationship (SAR) of seventy-eight compounds active against two pancreatic cancer cell lines. Our comprehensive evaluation of these compounds utilizes SAR that allow us to evaluate which features of potent compounds play a key role in their cytotoxicity. Th...

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Autori principali: Pan, Po-Shen, Vasko, Robert C., Lapera, Stephanie A., Johnson, Victoria A., Sellers, Robert P., Lin, Chun-Chieh, Pan, Chung-Mao, Davis, Melinda R., Ardi, Veronica C., McAlpine, Shelli R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774256/
https://ncbi.nlm.nih.gov/pubmed/19643615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.07.017
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