Loading...

Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine

AAA+ proteases are ATP-fueled machines that bind protein substrates via a degradation tag, unfold the molecule if necessary, and then translocate the polypeptide into a chamber for proteolysis. Tag recognition is normally viewed as a passive reaction. By contrast, for the AAA+ Lon protease, we show...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Gur, Eyal, Sauer, Robert T.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774003/
https://ncbi.nlm.nih.gov/pubmed/19841274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910392106
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!