Matrix Metalloproteinase-14 Mediates a Phenotypic Shift in the Airways to Increase Mucin Production

Rationale: Induced mainly by cigarette smoking, chronic obstructive pulmonary disease (COPD) is a global public health problem characterized by progressive difficulty in breathing and increased mucin production. Previously, we reported that acrolein levels found in COPD sputum could activate matrix...

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Detalhes bibliográficos
Main Authors: Deshmukh, Hitesh S., McLachlan, Anne, Atkinson, Jeffrey J., Hardie, William D., Korfhagen, Thomas R., Dietsch, Maggie, Liu, Yang, Di, Peter Y. P., Wesselkamper, Scott C., Borchers, Michael T., Leikauf, George D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
B. Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773913/
https://ncbi.nlm.nih.gov/pubmed/19661247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200903-0328OC
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