CD8(+) T Cells Contribute to Macrophage Accumulation and Airspace Enlargement Following Repeated Irritant Exposure

BACKGROUND: Persistent macrophage accumulation and alveolar enlargement are hallmark features of chronic obstructive pulmonary disease (COPD). A role for CD8(+) lymphocytes in the development of COPD is suggested based on observations that this T cell subset is increased in the airways and parenchym...

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Hlavní autoři: Borchers, Michael T., Wesselkamper, Scott C., Harris, Nathaniel L., Deshmukh, Hitesh, Beckman, Erin, Vitucci, Mark, Tichelaar, Jay W., Leikauf, George D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140237/
https://ncbi.nlm.nih.gov/pubmed/17950725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2007.08.020
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