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Chronic Cigarette Smoke Exposure Generates Pathogenic T Cells Capable of Driving COPD-like Disease in Rag2(−/−) Mice

Rationale: Pathogenic T cells drive, or sustain, a number of inflammatory diseases. Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease associated with the accumulation of activated T cells. We previously demonstrated that chronic cigarette smoke (CS) exposure causes oligocl...

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Autori principali: Motz, Gregory T., Eppert, Bryan L., Wesselkamper, Scott C., Flury, Jennifer L., Borchers, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891493/
https://ncbi.nlm.nih.gov/pubmed/20133926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200910-1485OC
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